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Optimal cut‐off score of the Edinburgh Postnatal Depression Scale for major depressive episode during pregnancy in Japan
Author(s) -
Usuda Kentaro,
Nishi Daisuke,
Okazaki Emi,
Makino Miyuki,
Sano Yo
Publication year - 2017
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/pcn.12562
Subject(s) - edinburgh postnatal depression scale , pregnancy , depression (economics) , major depressive episode , medicine , gestational age , receiver operating characteristic , population , obstetrics , gestation , antenatal depression , psychiatry , pediatrics , depressive symptoms , psychology , anxiety , cognition , macroeconomics , environmental health , biology , economics , genetics
Aim Depression during pregnancy adversely affects both mother and child. As antenatal depression is a predictor of postnatal depression, early detection might prevent postnatal depression. The Edinburgh Postnatal Depression Scale (EPDS) is frequently used during the perinatal period, but the cut‐off score during pregnancy has not been verified for the Japanese population. We aimed to clarify the optimal EPDS cut‐off score in mid‐pregnancy in Japan. Methods We recruited pregnant women aged 20 years or older at 12–24 gestational weeks and those who scored ≥9 on the EPDS were invited to participate in this study. In parallel with the EPDS, the Japanese version of the Mini‐International Neuropsychiatric Interview was administered to determine diagnosis of major depressive episode. We then calculated the receiver–operator curve, sensitivity and specificity, and positive and negative predictive values for the EPDS. Results All 210 participants were in the second trimester except for one (12 gestational weeks). Twenty participants were diagnosed with major depressive episode. With a cut‐off score set at 13 points, the area under the curve was 0.956; sensitivity and specificity were 90.0% and 92.1% [Correction added on 10 November 2017, after first online publication: The percentage for specificity has been corrected from 79.0% to 92.1%.], respectively; and positive and negative predictive values were 54.5% and 98.9%, respectively. Conclusion To our knowledge, this is the first study to clarify the optimal EPDS cut‐off score in the second trimester for Japan. This finding will be helpful for appropriate screening for antenatal depression in Japan.