Premium
Comparison of the 32‐item Hypomania Checklist, the 33‐item Hypomania Checklist, and the Mood Disorders Questionnaire for bipolar disorder
Author(s) -
Feng Yuan,
Wang YuanYuan,
Huang Wei,
Ungvari Gabor S.,
Ng Chee H.,
Wang Gang,
Yuan Zhen,
Xiang YuTao
Publication year - 2017
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/pcn.12506
Subject(s) - hypomania , major depressive disorder , bipolar disorder , medicine , psychiatry , mood , checklist , bipolar ii disorder , psychology , mood disorders , clinical psychology , mania , anxiety , cognitive psychology
Aim Bipolar disorder ( BD ) is frequently misdiagnosed as major depressive disorder ( MDD ) and hence reliable and culturally appropriate screening tools are needed. This study compared the 32‐item Hypomania Checklist ( HCL ‐32), the 33‐item Hypomania Checklist ( HCL ‐33), and the Mood Disorders Questionnaire ( MDQ ) for BD . Methods Altogether, 350 depressed patients were included. The HCL ‐32, HCL ‐33, and MDQ were completed by patients to identify manic and/or hypomanic symptoms. The sensitivity, specificity, positive predictive value ( PPV ), negative predictive value ( NPV ), and area under the curve among the HCL ‐32, HCL ‐33, and MDQ for BD and MDD were calculated and compared, using cut‐offs suggested by respective validation studies. Results Of the three scales, the MDQ had the highest sensitivity and NPV (sensitivity = 0.90, 0.81, and 0.90 for BD vs MDD , BD ‐I vs MDD , and BD ‐ II vs MDD , respectively; NPV = 0.78, 0.86, and 0.86 for BD vs MDD , BD ‐I vs MDD , and BD ‐ II vs MDD , respectively), while the HCL ‐33 had the highest specificity and PPV (specificity = 0.74, 0.69, and 0.66 for BD vs MDD , BD ‐I vs MDD , and BD ‐ II vs MDD , respectively; PPV = 0.74, 0.55, and 0.56 for BD vs MDD , BD ‐I vs MDD , and BD ‐ II vs MDD , respectively). Conclusion Compared to both HCL scales, the MDQ had higher sensitivity and lower specificity in screening for BD . These results contradict previous findings in Western populations. As a screening instrument for BD in Chinese clinical settings, the MDQ appears to be appropriate.