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Association of metabolic syndrome with atypical features of depression in J apanese people
Author(s) -
Takeuchi Takeaki,
Nakao Mutsuhiro,
Kachi Yuko,
Yano Eiji
Publication year - 2013
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1111/pcn.12104
Subject(s) - association (psychology) , depression (economics) , psychology , psychiatry , medicine , psychotherapist , macroeconomics , economics
Aim It has been controversial whether metabolic syndrome ( MetS ) is associated with depression. We aimed to clarify the correlation between MetS and depression, considering atypical features of depression. Methods Participants were 1011 J apanese men aged 20–59 years. MetS was diagnosed according to criteria set by the I nternational D iabetes F ederation. Clinical interviews for major depressive disorder ( MDD ) employed the DSM‐IV ; MDD was classified into atypical and non‐atypical types. The prevalence of MetS was compared between the groups with no MDD , atypical depression, and non‐atypical depression via trend analyses. Multiple logistic regression analyses examined the association of MetS with atypical depression and the features thereof. Results In total, 141 (14.0%) participants were diagnosed with MetS and 57 (5.6%) were diagnosed with MDD (14 had atypical and 43 had non‐atypical MDD ). The prevalence of MetS was the highest in the group with atypical depression, followed by the non‐atypical depression and no MDD groups, respectively, with a marginally significant trend ( P = 0.07). The adjusted odds ratios of MetS associated with depression were 3.8 (95% confidence interval [ CI ] 1.1–13.2) for atypical depression and 1.6 (95% CI 0.7–3.6) for non‐atypical depression. Among the five features of atypical depression, only hyperphagia was significantly related to MetS (odds ratio 2.7, 95% CI 1.8–4.1). Conclusion There was a positive association between MetS and atypical depression, but not between MetS and non‐atypical depression. Specifically, hyperphagia seems to be an important factor affecting the correlation between MetS and atypical depression.