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Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting
Author(s) -
van Geel Nanja,
Wolkerstorfer Albert,
Ezzedine Khaled,
Pandya Amit G.,
Bekkenk Marcel,
Grine Lynda,
Van Belle Sarah,
Lommerts Janny E.,
Hamzavi Iltefat,
Harris John E.,
Eleftheriadou Viktoria,
Esmat Samia,
Kang Hee Young,
Kumarasinghe Prasad,
Lan ChengChe E.,
Parsad Davinder,
Raboobee Noufal,
Flora Xiang Leihong,
Suzuki Tamio,
Prinsen Cecilia A.,
Taieb Alain,
Picardo Mauro,
Speeckaert Reinhart
Publication year - 2019
Publication title -
pigment cell and melanoma research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.618
H-Index - 105
eISSN - 1755-148X
pISSN - 1755-1471
DOI - 10.1111/pcmr.12784
Subject(s) - vitiligo , intraclass correlation , inter rater reliability , medicine , reimbursement , scale (ratio) , dermatology , construct validity , clinical psychology , rating scale , statistics , psychometrics , mathematics , cartography , health care , geography , economics , economic growth
Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5‐point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non‐segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.