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Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities
Author(s) -
Eroglu Zeynep,
Holmen Sheri L.,
Chen Qing,
Khushalani Nikhil I.,
Amaravadi Ravi,
Thomas Reena,
Ahmed Kamran A.,
Tawbi Hussein,
Chandra Sunandana,
Markowitz Joseph,
Smalley Inna,
Liu James K. C.,
Chen Yian Ann,
Najjar Yana G.,
Karreth Florian A.,
AbateDaga Daniel,
Glitza Isabella C.,
Sosman Jeffrey A.,
Sondak Ver K.,
Bosenberg Marcus,
Herlyn Meenhard,
Atkins Michael B.,
Kluger Harriet,
Margolin Kim,
Forsyth Peter A.,
Davies Michael A.,
Smalley Keiran S. M.
Publication year - 2019
Publication title -
pigment cell and melanoma research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.618
H-Index - 105
eISSN - 1755-148X
pISSN - 1755-1471
DOI - 10.1111/pcmr.12771
Subject(s) - summit , melanoma , medicine , translational research , central nervous system , metastasis , cancer , neuroscience , cancer research , pathology , biology , geography , cartography
In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.