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Links between S chwann cells and melanocytes in development and disease
Author(s) -
Van Raamsdonk Catherine D.,
Deo Mugdha
Publication year - 2013
Publication title -
pigment cell and melanoma research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.618
H-Index - 105
eISSN - 1755-148X
pISSN - 1755-1471
DOI - 10.1111/pcmr.12134
Subject(s) - neural crest , schwann cell , microbiology and biotechnology , biology , meninges , neuroscience , regeneration (biology) , central nervous system , anatomy , pathology , medicine , embryo
Summary Melanocytes are pigment‐producing cells that reside in the skin, eyes, ears, heart, and central nervous system meninges of mammals. Schwann cells are glial cells, which closely associate with peripheral nerves, myelinating, and sheathing them. Melanocytes and S chwann cells both arise from the neural crest during development, and some melanocytes arise directly from S chwann cell precursors lining developing spinal nerves. In this review, we explore the connections between melanocytes and S chwann cells in development and transformation.