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Network analysis for gene discovery in plant‐specialized metabolism
Author(s) -
HIGASHI YASUHIRO,
SAITO KAZUKI
Publication year - 2013
Publication title -
plant, cell and environment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.646
H-Index - 200
eISSN - 1365-3040
pISSN - 0140-7791
DOI - 10.1111/pce.12069
Subject(s) - computational biology , plant metabolism , gene regulatory network , genomics , network analysis , functional genomics , metabolomics , biology , gene , biological network , data science , bioinformatics , computer science , gene expression , genome , genetics , engineering , rna , electrical engineering
Recent omics technologies provide information on multiple components of biological networks. Web‐based data mining tools are continuously being developed. Because genes involved in specialized (secondary) metabolism are often co‐ordinately regulated at the transcriptional level, a number of gene discovery studies have been successfully conducted using network analysis, especially by integrating gene co‐expression network analysis and metabolomic investigation. In addition, next‐generation sequencing technologies are currently utilized in functional genomics investigations of A rabidopsis and non‐model plant species including medicinal plants. Systems‐based approaches are expected to gain importance in medicinal plant research. This review discussed network analysis in A rabidopsis and gene discovery in plant‐specialized metabolism in non‐model plants.