Open Accessm 6 A‐mediated regulation of crop development and stress responses
Author(s) -
Zhou Leilei,
Gao Guangtong,
Tang Renkun,
Wang Weihao,
Wang Yuying,
Tian Shiping,
Qin Guozheng
Publication year - 2022
Publication title -
plant biotechnology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.525
H-Index - 115
eISSN - 1467-7652
pISSN - 1467-7644
DOI - 10.1111/pbi.13792
Subject(s) - biology , crop , plant development , computational biology , agronomy , genetics , gene
Summary Dynamic chemical modifications in eukaryotic messenger RNAs (mRNAs) constitute an essential layer of gene regulation, among which N 6 ‐methyladenosine (m 6 A) was unveiled to be the most abundant. m 6 A functionally modulates important biological processes in various mammals and plants through the regulation of mRNA metabolism, mainly mRNA degradation and translation efficiency. Physiological functions of m 6 A methylation are diversified and affected by intricate sequence contexts and m 6 A machineries. A number of studies have dissected the functional roles and the underlying mechanisms of m 6 A modifications in regulating plant development and stress responses. Recently, it was demonstrated that the human FTO‐mediated plant m 6 A removal caused dramatic yield increases in rice and potato, indicating that modulation of m 6 A methylation could be an efficient strategy for crop improvement. In this review, we summarize the current progress concerning the m 6 A‐mediated regulation of crop development and stress responses, and provide an outlook on the potential application of m 6 A epitranscriptome in the future improvement of crops.