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Dynamic Mechanical Allodynia—One Clinical Sign, Several Mechanisms: Five Illustrative Cases
Author(s) -
Buonocore Michelangelo,
Demartini Laura,
Aloisi Anna Maria,
Bonezzi Cesare
Publication year - 2016
Publication title -
pain practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 58
eISSN - 1533-2500
pISSN - 1530-7085
DOI - 10.1111/papr.12416
Subject(s) - allodynia , medicine , neuropathic pain , mechanism (biology) , nociception , anesthesia , neuroscience , hyperalgesia , psychology , philosophy , epistemology , receptor
Pain evoked by tangential movement across the skin is usually defined as dynamic mechanical allodynia ( DMA ). Some patients complain of DMA as troublesome as spontaneous pain and refer a marked interfering with activities of daily living and sleep. Pathophysiology of DMA is complex and can be related to several mechanisms, both nociceptive and neuropathic. Five exemplificative clinical cases of DMA are presented, each associated to a possible specific mechanism: injured skin DMA , peri‐injured skin DMA , far injury DMA , nerve‐confined DMA and fear DMA (pseudo allodynia). The identification of these subcategories of DMA can stimulate further studies aimed at evaluating the usefulness of a mechanism‐based therapy for the different clinical forms of DMA .