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Neuropathic Pain and Pharmacological Treatment
Author(s) -
Jongen Joost L. M.,
Hans Guy,
Benzon Honorio T.,
Huygen Frank,
Hartrick Craig T.
Publication year - 2014
Publication title -
pain practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 58
eISSN - 1533-2500
pISSN - 1530-7085
DOI - 10.1111/papr.12085
Subject(s) - neuropathic pain , medicine , polypharmacy , population , lesion , quality of life (healthcare) , intervention (counseling) , anesthesia , intensive care medicine , surgery , psychiatry , environmental health , nursing
Neuropathic pain is a serious chronic condition strongly affecting quality of life, which can be relieved but cannot be cured. Apart from symptomatic management, treatment should focus on the underlying disorder. The estimated prevalence is at least 1% to 5% of the general population. Neuropathic pain is characterized both by spontaneous and evoked pain. A diagnosis of neuropathic pain can usually be established based solely on history and neurological examination. Ancillary investigations may include EMG and computerized tomography/magnetic resonance imaging scans, depending on the localization of the suspected lesion. A limited number of agents, primarily directed at symptom control, are currently approved for use in neuropathic pain. A mechanism‐based approach to pharmacological intervention supports the use of polypharmacy in neuropathic pain.