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Dexmedetomidine infusion overdose during anesthesia: A case report
Author(s) -
Li Christine,
Clifford Michael
Publication year - 2020
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/pan.13801
Subject(s) - dexmedetomidine , medicine , bradycardia , anesthesia , inotrope , heart rate , sedation , blood pressure , cardiology
A 12‐kg infant was given intravenous dexmedetomidine 0.2 µg kg ‐1 min ‐1 as an adjunct for general anesthesia. The 60‐fold increase in dexmedetomidine infusion rate caused a biphasic response with initial hypertension followed by bradycardia and hypotension requiring inotropic support. No postoperative or long‐term sequelae were noted. Dexmedetomidine infusion is usually delivered as µg kg ‐1 h ‐1 .