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Anaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion
Author(s) -
Chiem Jennifer,
Ivanova Iskra,
Parker Andrew,
Krengel Walter,
Jimenez Nathalia
Publication year - 2017
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/pan.13141
Subject(s) - medicine , tranexamic acid , anaphylaxis , anaphylactic reaction , anesthesia , nausea , spinal fusion , surgery , allergy , blood loss , immunology
Summary Tranexamic acid is an anti‐fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72‐year‐old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.