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Hemodynamic instability during anesthesia in an adolescent with L oeys‐ D ietz syndrome: a case report
Author(s) -
Bunting Alexandra C.,
Bould M. Dylan
Publication year - 2014
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/pan.12511
Subject(s) - medicine , hemodynamics , anesthesia , orthopedic surgery , aortic root , antagonist , cardiology , surgery , aorta , receptor
Summary We present a case of a 12‐year‐old male with L oeys‐ D ietz syndrome ( LDS ), a rare life‐threatening genetic disorder. Multiple manifestations of LDS were present, including easy bruising, aortic root dilatation, multiple areas of vessel tortuosity, and joint laxity. The patient's medications included a beta‐blocker and an angiotensin II receptor antagonist for prophylaxis against further aortic root dilatation due to his LDS . He experienced intraoperative hemodynamic instability and became pulseless during an orthopedic procedure, which had to be abandoned. Anesthesia was reattempted 2 days after cessation of the patient's antihypertensive medications and was successful with only minor postoperative hypertension.