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Vasovagal syncope and severe bradycardia following intranasal dexmedetomidine for pediatric procedural sedation
Author(s) -
Patel Vinit J.,
Ahmed Sheikh S.,
Nitu Mara E.,
Rigby Mark R.
Publication year - 2014
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1111/pan.12368
Subject(s) - medicine , dexmedetomidine , bradycardia , anesthesia , sedation , vital signs , nasal administration , vasovagal syncope , abnormality , heart rate , blood pressure , reflex , psychiatry , immunology
Summary We report syncope and bradycardia in an 11‐year‐old girl following administration of intranasal dexmedetomidine for sedation for a voiding cystourethrogram. Following successful completion of VCUG and a 60‐min recovery period, the patient's level of consciousness and vital signs returned to presedation levels. Upon leaving the sedation area, the patient collapsed, with no apparent inciting event. The patient quickly regained consciousness and no injury occurred. The primary abnormality found was persistent bradycardia, and she was admitted to the hospital for telemetric observation. The bradycardia lasted ~2 h, and further cardiac workup revealed no underlying abnormality. Unanticipated and previously unreported outcomes may be witnessed as we expand the use of certain sedatives to alternative routes of administration.

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