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Drug‐induced enterocolitis syndrome: Similarities and differences compared with food protein‐induced enterocolitis syndrome
Author(s) -
Mori Francesca,
Liccioli Giulia,
Fuchs Oliver,
Barni Simona,
Giovannini Mattia,
Sarti Lucrezia,
Novembre Elio,
Caubet JeanChristoph
Publication year - 2021
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/pai.13491
Subject(s) - medicine , enterocolitis , drug , intensive care medicine , pediatrics , disease , psychiatry
In 2014, drug‐induced enterocolitis syndrome (DIES) was described for the first time. It is still a poorly known disease with symptoms that typically resemble those of food protein–induced enterocolitis syndrome (FPIES). To date, six more cases of DIES have been described and new clinical diagnostic criteria have been proposed based on those in the international guidelines for FPIES. In this paper, the authors describe three more cases of DIES. In addition, similarities and differences with FPIES have been deeply analyzed. To date, several unanswered questions need to be addressed, but clinicians must be instructed how to identify DIES, in order to make an allergy workup and give definite therapeutic indications to patients, especially in children where DIES seems to be more frequent.