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Individualized immunoglobulin treatment in pediatric patients with primary humoral immunodeficiency disease
Author(s) -
Patel Niraj C.
Publication year - 2018
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/pai.12923
Subject(s) - medicine , primary immunodeficiency , common variable immunodeficiency , antibody , dosing , immunology , adverse effect , disease , immunodeficiency , intensive care medicine , pediatrics , immune system
Primary immunodeficiency diseases ( PIDD ) are a group of genetic conditions that are generally considered to be under‐diagnosed, and gaps may exist in the knowledge of treatment options. This review focuses on the diagnosis of pediatric patients with primary antibody deficiency and considerations for treatment with immunoglobulin (IgG) to optimize multiple dosing variables and minimize adverse events. The possibility of individualizing IgG therapy in clinical practice represents, in this field, the next pivotal step with the goal of improving the quality of life of pediatric patients with PIDD .