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Treatment of allergic children – Where is the progress (for the practicing allergist)?
Author(s) -
Wert A. F.,
Posa D.,
Tsilochristou O.,
Schwerk N.
Publication year - 2016
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/pai.12653
Subject(s) - medicine , food and drug administration , asthma , intervention (counseling) , medline , family medicine , alternative medicine , intensive care medicine , pediatrics , immunology , environmental health , psychiatry , pathology , political science , law
For any kind of therapeutic intervention in allergic diseases such as environmental control, pharmacological, or immunomodulating treatment including educational programs, children are addressed separately from adults. Health authorities like the Food and Drug Administration in the United States of America or the European Medicine Agency in Europe request a specific ‘Pediatric investigational plan’ with studies addressing dose–response relationship, safety, and efficacy for infants, children, and adolescents. During the last 2 years, promising advances have been reported for the treatment of a variety of allergic and immunologic disorders. This review summarizes the progress in the treatment of pediatric asthma and allergic diseases, based on publications of approximately the last 2.5 years (end of 2013 until May 2016) in and beyond this journal. Meanwhile, it highlights areas with promising novel therapeutic approaches, which are likely to change treatment for allergic children in the near future.