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Arrhythmia profile and ablation‐outcome in elderly women with atrial fibrillation undergoing first catheter ablation
Author(s) -
Natale Veronica,
Mohanty Sanghamitra,
Trivedi Chintan,
Baqai Faiz M.,
Gallinghouse Joseph,
Della Rocca Domenico Giovanni,
Gianni Carola,
MacDonald Bryan,
Mayedo Angel,
Burkhardt John David,
Gallinghouse Gerald J.,
AlAhmad Amin,
Horton Rodney,
Bassiouny Mohamed,
Di Biase Luigi,
Natale Andrea
Publication year - 2021
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.14223
Subject(s) - medicine , ablation , atrial fibrillation , catheter ablation , cardiology , group b , surgery
Background This study evaluated the arrhythmia profile and ablation outcome in women with atrial fibrillation (AF) aged ≥75 years. Methods A total of 573 consecutive female patients undergoing first AF ablation were classified into group 1: ≥75 years (n = 221) and group 2: < 75 years (n = 352). Isolation of PVs, posterior wall and superior vena cava was performed in all. Non‐PV triggers from other areas were ablated based on operator's discretion. Results Group 1 had higher prevalence of hypertension (154 (69.7%) vs. 188 (53.4%), p < .001) and non‐paroxysmal AF (136 (61.5%) vs. 126 (35.8%), p < .001). Non‐PV triggers were detected in 194 (87.8%) patients from group 1 and 143 (40.6%) from group 2 ( p < .001) and were ablated in 152 (68.8%) and 114 (32.4%) from group 1 and 2 respectively. Remaining patients (group 1: 69/221 and group 2: 238/352) received no additional ablation. At 4 years, 109 (49.3%) and 185 (52.6%) from group 1 and 2, respectively, were arrhythmia‐free, p = .69. When stratified by ablation‐strategy, success‐rate was similar across groups in patients receiving non‐PV trigger ablation (96 (63.2%) in group 1 and 76 (66.7%) in group 2, p = .61), whereas it was significantly lower in group 1 patients not receiving additional ablation compared to those from group 2 (13 (18.8%) vs. 109 (45.8%), p < .001). Conclusion Non‐paroxysmal AF was more common in women aged ≥75 years. Furthermore, significantly higher number of non‐PV triggers were detected in elderly women and ablation of those provided similar ablation success as that in women aged < 75 years.