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Catheter ablation of paroxysmal atrial fibrillation using high‐density mapping‐guided substrate modification
Author(s) -
Zhou Wei,
Wang Long,
Zhou Bo,
Wu Lirong
Publication year - 2018
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.13524
Subject(s) - medicine , atrial fibrillation , pulmonary vein , catheter ablation , ablation , cardiology , paroxysmal atrial fibrillation , catheter , surgery , anesthesia
Abstract Background This study aimed to evaluate the effect of substrate modification in paroxysmal atrial fibrillation (AF) patients prior to circumferential pulmonary vein isolation (CPVI). Methods Patients without left atrial low‐voltage and/or scar areas were defined as Group A. Patients with left atrial low‐voltage and/or scar areas underwent regular CPVI (Group B) or substrate modification after CPVI (Group C). The procedural success rate and differences in the left atrial diameter (LAD) among groups were compared at 1 year postoperatively. Results The procedural success rate in Group C was comparable to that in Group A ( P > 0.05) and was significantly higher than that in Group B ( P < 0.01). The LAD of patients in Groups A and C significantly decreased at 1 year postoperatively compared to that prior to the surgery ( P < 0.05). However, no significant difference was noted in Group B. Conclusions Our study demonstrated that substrate modification could contribute to the single catheter ablation surgery success rate in patients with paroxysmal AF and narrow LAD.