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Internal Cardioverter Defibrillator Indications and Therapies after Atrial Baffle Procedure for d‐Transposition of the Great Arteries: A Multicenter Analysis
Author(s) -
BACKHOFF DAVID,
KERST GUNTER,
PETERS ANDREA,
LÜDEMANN MONIKA,
FRISCHE CHRISTIAN,
HORNDASCH MICHAELA,
HESSLING GABRIELE,
PAUL THOMAS,
KRAUSE ULRICH
Publication year - 2016
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.12933
Subject(s) - medicine , implantable cardioverter defibrillator , atrial fibrillation , cardiology , ventricular tachycardia , sudden cardiac death , great arteries , atrial tachycardia , population , cohort , surgery , heart disease , catheter ablation , environmental health
Background Sudden cardiac death (SCD) is the most important cause of late mortality after atrial baffle procedure for d‐transposition of the great arteries (d‐TGA). Experience with internal cardioverter defibrillator (ICD) therapy in this population is limited. We conducted a multicenter cohort study to determine the current state of ICD therapy in individuals after atrial baffle procedure. Methods Demographic and clinical data as well as data on device implantation, programming, ICD discharges, and complications after atrial baffle procedure for d‐TGA from four German centers were analyzed retrospectively. Results ICD implantation was undertaken in 33 subjects. ICD implantation was undertaken as primary prevention in 29 (88%) and secondary prevention in four (12%) individuals. There were 21 (64%) subjects with atrial reentrant tachycardia (IART). During a median follow‐up of 4.8 years, seven appropriate ICD therapies were delivered in three (10%) individuals with primary prevention indication. No appropriate shocks were documented in subjects with secondary prevention indication. A total of 12 inappropriate ICD discharges occurred in eight (24%) individuals due to IART (n = 6) or lead failure (n = 2). ICD‐related complications were noted in seven individuals (21%): lead dislodgement/failure in five (15%) and ICD infection in two subjects (6%). Conclusions The majority of individuals received an ICD for primary prevention of SCD, thus representing a liberal attitude of physicians for ICD implantation. During a median follow‐up of 4.8 years, the rate of appropriate ICD therapies was low and clearly exceeded by inappropriate ICD discharges. Lead failure and IART were present in >20% of the individuals and were frequent reasons for inappropriate ICD discharges. Facing these results, rigorous treatment of IART and careful ICD programming seems mandatory.