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Relationship between Neurocardiogenic Syncope and Ventricular Repolarization
Author(s) -
SUCU MURAT,
OZER ORHAN,
DAVUTOGLU VEDAT,
ERCAN SULEYMAN,
YUCE MURAT,
COSKUN FATMA YILMAZ
Publication year - 2015
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.12599
Subject(s) - medicine , qt interval , ventricular repolarization , cardiology , repolarization , long qt syndrome , anesthesia , electrophysiology
Background We aimed to analyze ventricular repolarization in neurocardiogenic syncope (NCS) patients by using T‐peak‐T‐end interval, T‐peak‐T‐end/QT ratio, T‐peak‐T‐end/QTc ratio and corrected QT interval (QTc), QT dispersion (QTd), QT index (QTI) and corrected QT interval index (QTcI) comparing with the corrected JT dispersion (JTcd), and corrected JT (JTc) and the corrected JT interval index (JTcI), by inspecting ventricular activation until termination of repolarization. These parameters are used as an index of potential ventricular arrhythmogenesis. Methods We have studied patients with head‐up tilt table test (HUTT) (+) (33 patients; mean age: 28 ± 11 years) and HUTT (–) as control group (33 patients; mean age: 30 ± 11 years). In all patients, T‐peak‐T‐end interval, T‐peak‐T‐end/QT ratio, T‐peak‐T‐end/QTc ratio, QT, QTd, QTI, QTc, QTcI, JTd, JTc, and JTcI were measured on electrocardiogram. Results The following parameters were statistically significant between groups: QTd (22.72 ± 17.54 msn; 11.21 ± 13.40 msn; P = 0.004), QTc (424.27 ± 33.75 msn; 403.66 ± 38.08 msn; P = 0.023), QTcI (114.09 ± 14, 29%; 106.71 ± 15.33%, P = 0.047), and QTI (100.72 ± 7.19%; 97.14 ± 7.13%, P = 0.046). Furthermore, T‐peak‐T‐end interval was significantly prolonged in the study group (93.78 ± 20.27 msn; 81.21 ± 11.66 msn; P = 0.003). T‐peak‐T‐end/QT ratio was significantly higher in the study group (0.24 ± 0.04 msn; 0.22 ± 0.04 msn; P = 0.030). T‐peak‐T‐end/QTc ratio was significantly higher in the study group (0.22 ± 0.04 msn; 0.20 ± 0.03 msn; P = 0.015). The JTc and JTd were also significantly higher in the study group ([103.00 ± 9, 72%; 95.44 ± 10.26%, P = 0.003], [27.57 ± 16.01 msn; 10.45 ± 16.08 msn; P < 0.001], respectively). Conclusions Electrocardiographic ventricular repolarization parameters including T‐peak‐T‐end interval, T‐peak‐T‐end/QT ratio, T‐peak‐T‐end/QTc ratio, QTc, QTd, QTI, QTcI, JTc, JTd, and JTI are prolonged in NCS.