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Association between Left‐Handedness and Cardiac Autonomic Function in Healthy Young Men
Author(s) -
İŞCEN SINAN,
ÖZENÇ SALIM,
TAVLASOGLU URAT
Publication year - 2014
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.12365
Subject(s) - medicine , cardiology , asymptomatic , blood pressure , qrs complex , heart rate , statistical significance , diastole , body mass index
Background Effects of nonright‐handedness on risk for sudden death associated with coronary artery disease via sympathetic imbalance contributed to ventricular arrhythmogenesis previously have been demonstrated. This study hypothesized that left‐handedness might be associated with cardiac autonomic functions in healthy young men. The aim of this study was to examine the association between left‐handedness and cardiac autonomic functions in healthy young men. Methods A total of 992 asymptomatic young male subjects underwent routine health checkup between May 2012 and July 2013, and were included in this study. All were submitted to a standard protocol that included a complete clinical examination, laboratory evaluation, 12‐lead electrocardiogram, and 2D‐echocardiogram. Fifty‐two subjects were left‐handed; 32 subjects had abnormal QRS‐T angle. Statistical analyses were performed using statistical package SPSS 15.0 (IBM Corp., Armonk, NY, USA) and statistical significance was assessed at the two‐tailed 0.05 threshold. Results A total of 52 (5%) subjects were left‐handed; 32 (3%) subjects had an abnormal frontal QRS‐T angle. The mean age, body mass index, systolic blood pressure, diastolic blood pressure, high‐density lipoprotein cholesterol, low‐density lipoprotein cholesterol, triglycerides, fasting glucose, current smoking, estimated glomerular filtration rate, hemoglobin, leukocyte count, platelet count, and echocardiographic parameters were not different between two groups. But subjects with left‐handedness had greater prevalence of abnormal QRS‐T angle. The left‐handedness group had 18 subjects with abnormal QRS‐T angle (34%) and the right‐handedness group had 14 subjects with abnormal QRS‐T angle (1.4%). The difference between two groups was significant (P < 0.001). Conclusion In this study, there was a significant association between left‐handedness and abnormal QRS‐T angle in healthy young subjects.