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Quality of Life and Functional Capacity after Long‐Term Right Ventricular Pacing in Pediatrics and Young Adults with Congenital Atrioventricular Block
Author(s) -
SILVA KÁTIA REGINA,
COSTA ROBERTO,
OLIVEIRA ROBERTO MÁRCIO,
LACERDA MARIANNA SOBRAL,
UN HUANG ADRIANA I,
ROSSI MARINA BERTELLI,
CREVELARI ELIZABETH SARTORI,
TAMAKI WAGNER TETSUJI,
FILHO MARTINO MARTINELLI,
PIETROBON RICARDO
Publication year - 2013
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/pace.12258
Subject(s) - medicine , quality of life (healthcare) , ejection fraction , atrioventricular block , cardiology , vitality , health related quality of life , pediatrics , physical therapy , heart failure , philosophy , nursing , theology , disease
Background Although several studies have demonstrated deleterious consequences of chronic right ventricular (RV) pacing on ventricular function and synchronicity, its effects on health‐related quality of life (HRQoL) and functional exercise capacity remain uncertain. We aimed to evaluate the effect of RV pacing on HRQoL and functional capacity of children and young adults with congenital complete atrioventricular block (CCAVB). Methods We included 66 consecutive subjects with RV cardiac pacemaker due to CCAVB and under clinical follow‐up for more than 1 year. Multidimensional HRQoL scores were evaluated by Short Form‐36 Health Survey (SF‐36) and Child Health Questionnaire‐Parent Form 50 (CHQ‐PF50). Functional capacity was tested by a 6‐minute walk distance test (6MWDT). Association analysis was performed to examine if any demographic and clinical characteristics were associated with lower HRQoL scores and shorter distances at the 6MWDT . Results Domains presenting lower HRQoL scores were vitality (64.0 ± 17.3), mental health (67.3 ± 8.0), role emotional (69.7 ± 35.8) in the SF‐36 questionnaire; general health perceptions (61.3 ± 8.3), general behavior (61.9 ± 15.6), parental impact—emotional (67.7 ± 28.7) in the CHQ‐PF50. Female gender (P = 0.009), left ventricular ejection fraction lower than 55% (P = 0.013), cardiovascular drugs (P = 0.003) were significantly associated with lower HRQoL scores. Average distance traveled during the 6MWDT was 539.8 ± 82.9 m. The 6MWDT showed significant association with age (P = 0.006) and cardiovascular drugs (P = 0.024) . Conclusions Chronic RV pacing did not affect the HRQoL and physical capacity of pediatrics and young subjects. Female gender, ventricular function, and cardiovascular drugs were associated with lower HRQoL scores. Older subjects walked shorter distances in the 6MWDT, as well as subjects who were taking cardiovascular drugs .