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Combined orthodontic and surgical treatment in PTH 1R ‐negative ‘primary failure of eruption’‐like anomalies: report of two cases with satisfactory long‐term response to traction
Author(s) -
Perrin J.P.,
Millot G.,
Isidor B.,
Salagnac J.M.,
Corre P.,
Khonsari R.H.
Publication year - 2019
Publication title -
oral surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.156
H-Index - 11
eISSN - 1752-248X
pISSN - 1752-2471
DOI - 10.1111/ors.12410
Subject(s) - medicine , tooth eruption , ankylosis , presentation (obstetrics) , dentistry , dental anomalies , orthodontics , surgery , molar
Primary failure of eruption ( PFE ) is a sporadic or inherited disorder of dental eruption that can be caused by mutations in the PTH 1R gene. PFE typically manifests as a severe posterior open bite. Orthodontic treatment is considered ineffective in PFE . Case presentation Here, we report two unrelated PTH 1R ‐negative cases of severe eruption disorders presenting several of the typical clinical features of PFE , and where we tracted the impacted teeth using Bollard bone anchors. Management We managed to obtain a satisfactory occlusion in both cases without extended ankylosis induced by the orthodontic movements based on bone anchors. Outcome These cases underline the need for a better understanding of the genetics of dental eruption disorders related to PFE before establishing strict clinical guidelines ruling out potentially efficient orthodontic management protocols within the PFE spectrum.

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