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From corneal shape to ocular wavefront in eyes with aspheric IOL s: the feasibility of IOL customisation
Author(s) -
Jong Tim,
Canovas Carmen,
Weeber Henk,
Jansonius Nomdo M.
Publication year - 2016
Publication title -
ophthalmic and physiological optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.147
H-Index - 66
eISSN - 1475-1313
pISSN - 0275-5408
DOI - 10.1111/opo.12258
Subject(s) - zernike polynomials , wavefront , coma (optics) , spherical aberration , corneal topography , astigmatism , optics , ophthalmology , aberrations of the eye , mathematics , physics , cornea , medicine , lens (geology)
Purpose To determine if it is possible to predict the ocular wavefront aberrations of eyes with an aspheric IOL from the corneal shape and other readily available eye characteristics. A reliable prediction is a prerequisite for future IOL customisation. Methods Sixty pseudophakic eyes with aspheric IOL s of 60 patients were included. The corneal shape and the ocular wavefront aberrations were measured postoperatively with a Scheimpflug camera and an aberrometer, respectively. The elevation data of the anterior corneal surface were fitted by Zernike polynomials. Linear regression models for the Zernike coefficients describing the ocular wavefront aberrations up till the fourth order were determined, with as independent variables the Zernike coefficients describing the corneal shape, the eye (right/left), IOL power, and axial length. Results Linear regression equations with an explained variance (adjusted R ‐square) above 0.50 were found for five Zernike aberration terms: defocus ( z (2,0); adjusted R ‐square 0.90), the astigmatism terms (0.81 for oblique astigmatism [ z (2,−2)] and 0.88 for regular astigmatism [ z (2,2)]), vertical coma ( z (3,−1); 0.52), and spherical aberration ( z (4,0); 0.71). Conclusion The defocus, astigmatism, vertical coma, and spherical aberration terms of the ocular wavefront are strongly associated with the corneal shape in pseudophakic eyes and may thus be predicted from the corneal shape and other eye characteristics.