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Corneal cross‐linking – a review
Author(s) -
Meek Keith M,
Hayes Sally
Publication year - 2013
Publication title -
ophthalmic and physiological optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.147
H-Index - 66
eISSN - 1475-1313
pISSN - 0275-5408
DOI - 10.1111/opo.12032
Subject(s) - keratoconus , cornea , medicine , optometry , ophthalmology , clinical trial , pathology
Purpose To review cross‐linking the cornea using riboflavin and ultraviolet A light, which has been widely adopted, refined and applied in a range of corneal surgeries and pathologies where the strength of the cornea might be compromised. Recent findings A large number of clinical trials have been carried out, most of which have demonstrated that standard cross‐linking is a successful method to halt the progression of keratoconus or even aid regression. Summary This review describes our current understanding of the technique, focussing on how cross‐linking works, how the treatment is being optimised, the clinical results that have been reported to date and the potential use of the therapy in the treatment of other corneal disorders.