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Can oral health and oral‐derived biospecimens predict progression of dementia?
Author(s) -
Orr Miranda E.,
Reveles Kelly R.,
Yeh ChihKo,
Young Eric H.,
Han Xianlin
Publication year - 2020
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.13201
Subject(s) - dementia , oral health , oral hygiene , cognition , cognitive decline , medicine , disease , oral microbiome , dysbiosis , gerontology , psychiatry , dentistry , pathology
Growing evidence indicates that oral health and brain health are interconnected. Declining cognition and dementia coincide with lack of self‐preservation, including oral hygiene. The oral microbiota plays an important role in maintaining oral health. Emerging evidence suggests a link between oral dysbiosis and cognitive decline in patients with Alzheimer's disease. This review showcases the recent advances connecting oral health and cognitive function during aging and the potential utility of oral‐derived biospecimens to inform on brain health. Collectively, experimental findings indicate that the connection between oral health and cognition cannot be underestimated; moreover, oral biospecimens are abundant and readily obtainable without invasive procedures, which may help inform on cognitive health.