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Susceptibility of partially desalivated rats to erosive tooth wear by calcium‐supplemented beverages
Author(s) -
Aldosari MA,
Scaramucci T,
Liu SSY,
WarrickPolackoff JM,
Eckert GJ,
Hara AT
Publication year - 2018
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12740
Subject(s) - tooth wear , molar , dentistry , enamel paint , medicine , population , orthodontics , environmental health
Objectives To investigate the susceptibility of partially desalivated rats to erosive tooth wear ( ETW ); the anti‐erosive effect of a calcium‐supplemented beverage; and the quantification of ETW by microcomputed tomography (micro‐ CT ). Methods The study population consisted of thirty‐eight rats, divided into partially desalivated ( n = 19) and normal salivary flow ( n = 19). They were randomly allocated into three subgroups ( n = 6–7): A‐diet soda, B‐diet soda + calcium, C‐water (control). Solutions were provided ad libitum for 28 days, and the rats were euthanized afterwards. Each left hemi‐mandible was scanned using micro‐ CT for enamel volume (three molars) calculation. Visual analysis of photographs of the lingual surface of first molar s was performed independently by three blinded examiners. Data were statistically analysed (α = .05). Results Micro‐ CT revealed no significant differences between partially desalivated or normal groups. Rats consuming A had more enamel loss than those consuming B or C, which did not differ from each other. For visual analysis, desalivation did not affect ETW . Rats consuming C showed the lowest ETW , followed by B and then A, for both partially desalivated and normal rats. Spearman correlation between the two ETW quantification methods was −.65. Conclusions Partial desalivation did not increase ETW . Ca‐containing beverage prevented ETW . Micro‐ CT quantified ETW , although it was not as sensitive as visual analysis.