Immune reconstitution inflammatory syndrome in  HIV  infection: taking the bad with the good | Zendy

Wong CS | Zendy; Richards ES | Zendy; Pei L | Zendy; Sereti I | Zendy

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Immune reconstitution inflammatory syndrome in HIV infection: taking the bad with the good

Author(s) -

Wong CS,

Richards ES,

Pei L,

Sereti I

Publication year - 2017

Publication title -

oral diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.953

H-Index - 87

eISSN - 1601-0825

pISSN - 1354-523X

DOI - 10.1111/odi.12606

Subject(s) - immune reconstitution inflammatory syndrome , immune system , immunology , human immunodeficiency virus (hiv) , iris (biosensor) , medicine , antiretroviral therapy , inflammation , antigen , virology , viral load , computer science , computer security , biometrics

In this review, we will describe the immunopathogies of immune reconstitution inflammatory syndrome, IRIS . IRIS occurs in a small subset of HIV patient, initiating combination antiretroviral therapy ( ART ), where immune reconstitution becomes dysregulated, resulting in an overly robust antigen‐specific inflammatory reaction. We will discuss IRIS in terms of the associated coinfections: mycobacteria, cryptococci, and viruses.

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