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Immune reconstitution inflammatory syndrome in HIV infection: taking the bad with the good
Author(s) -
Wong CS,
Richards ES,
Pei L,
Sereti I
Publication year - 2017
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12606
Subject(s) - immune reconstitution inflammatory syndrome , immune system , immunology , human immunodeficiency virus (hiv) , iris (biosensor) , medicine , antiretroviral therapy , inflammation , antigen , virology , viral load , computer science , computer security , biometrics
In this review, we will describe the immunopathogies of immune reconstitution inflammatory syndrome, IRIS . IRIS occurs in a small subset of HIV patient, initiating combination antiretroviral therapy ( ART ), where immune reconstitution becomes dysregulated, resulting in an overly robust antigen‐specific inflammatory reaction. We will discuss IRIS in terms of the associated coinfections: mycobacteria, cryptococci, and viruses.