Premium
Elevated leukocyte count is associated with periodontitis in Korean adults: the 2012–2014 KNHANES
Author(s) -
Kwon YJ,
Jeon KJ,
Chung TH,
Lee YJ
Publication year - 2017
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12601
Subject(s) - quartile , periodontitis , national health and nutrition examination survey , medicine , odds ratio , confounding , confidence interval , logistic regression , population , gastroenterology , environmental health
Objective Both an elevated leukocyte count and periodontitis share well‐recognized associations with cardiometabolic diseases. This cross‐sectional study aimed to identify whether the leukocyte count is associated with periodontitis in a nationally representative Korean adult population. Materials and Methods Data from 9391 participants (3659 males and 5732 females) enrolled in 2012–2014 Korean National Health and Nutrition Examination Survey were analyzed. Leukocyte quartiles were categorized as follows: 3000 ≤ Q1 ≤ 4870, 4880 ≤ Q2 ≤5790, 5800 ≤ Q3 ≤ 6840, and 6850 ≤ Q4 ≤ 10000 cells/ μ l. Periodontitis was defined as scoring greater than or equal to ‘code 3’ in at least one site according to the WHO 's Community Periodontal Index. The odds ratios ( OR s) and 95% confidence intervals (95% CI s) for periodontitis in each leukocyte count quartile were calculated using multiple logistic regression analyses. Results The prevalence of periodontitis was directly correlated with increasing leukocyte quartiles: 19%, 20.4%, 24.3%, and 30.3%. Compared with the lowest leukocyte quartile group, the OR (95% CI ) for periodontitis of the highest leukocyte quartile was 1.558 (1.285–1.891) after controlling for confounding factors. Conclusion An elevated leukocyte count was positively associated with the presence of periodontitis.