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Establishing and managing a periodontal biobank for research: the sharing of experience
Author(s) -
Vaithilingam RD,
Safii SH,
Baharuddin NA,
KarenNg LP,
Saub R,
Ariffin F,
Ramli H,
Sharifuddin A,
Hidayat MFH,
Raman R,
Chan YK,
Rani NA,
Rahim RA,
Shahruddin N,
Cheong SC,
Bartold PM,
Zain RB
Publication year - 2015
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12267
Subject(s) - biobank , acknowledgement , periodontal disease , ethical issues , dental research , protocol (science) , sample (material) , data collection , medicine , informed consent , engineering ethics , dentistry , alternative medicine , pathology , engineering , bioinformatics , computer science , sociology , biology , social science , chemistry , computer security , chromatography
Periodontal bio‐repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the M alaysian P eriodontal D atabase and B iobank S ystem ( MPDBS ) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad‐based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the M alaysian O ral C ancer D atabase and T issue B ank S ystem ( MOCDTBS ). In the development of the MPDBS , challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders.