Immunomodulation regulates mesenchymal stem cell‐based bone regeneration | Zendy

Su Y | Zendy; Shi S | Zendy; Liu Y | Zendy

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Immunomodulation regulates mesenchymal stem cell‐based bone regeneration

Author(s) -

Su Y,

Shi S,

Liu Y

Publication year - 2014

Publication title -

oral diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.953

H-Index - 87

eISSN - 1601-0825

pISSN - 1354-523X

DOI - 10.1111/odi.12248

Subject(s) - mesenchymal stem cell , regeneration (biology) , regenerative medicine , stem cell , clinical uses of mesenchymal stem cells , immune system , medicine , biology , microbiology and biotechnology , bioinformatics , immunology , cellular differentiation , adult stem cell , biochemistry , gene

Mesenchymal stem cell ( MSC )‐based regenerative medicine represents a promising frontier for bone reconstruction. Significant efforts have been devoted to clarifying the capacities of MSC s to repair or reconstruct bone tissue. This review provides a concise summary of current knowledge pertaining to the possible mechanisms of MSC action in the regeneration of bone, with particular focus on the interplay between donor MSC s and host immune response in the process of new bone regeneration.

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