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Challenges in predicting which oral mucosal potentially malignant disease will progress to neoplasia
Author(s) -
Scully C
Publication year - 2014
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12208
Subject(s) - oral submucous fibrosis , medicine , basal cell , dermatology , oral cancers , disease , leukoplakia , dilemma , precancerous condition , oral mucosa , oral and maxillofacial pathology , pathology , cancer , dentistry , philosophy , epistemology
Probably the greatest challenge to those managing patients with oral diseases is the dilemma of attempting to predict which oral erythroplakias, leukoplakias, lichenoid and other potentially malignant mucosal disease ( PMD ) such as oral submucous fibrosis will progress to neoplasia – notably oral squamous cell carcinoma ( OSCC ). The paper reviews progress over the past decade and the application to the clinical situation.