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Morphometrical study of minor salivary gland in xerostomic patients with altered lipid metabolism
Author(s) -
Lukach L,
Maly A,
Zini A,
Aframian DJ
Publication year - 2014
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1111/odi.12195
Subject(s) - salivary gland , lipid metabolism , metabolism , medicine , physiology
Objective To evaluate the correlation between dyslipidemia in patients with oral dryness and the development of non‐specific histopathological findings in their labial salivary gland biopsies. Methods Thirty seven patients suffering from oral dryness (18 patients with dyslipidemia and 19 age‐matched patients with normal lipid blood levels) underwent labial salivary gland biopsy. Total acinar area ( TAA ), acinar cell number, acinar lumen area ( ALA ), duct lumen area ( DLA ), area occupied by cells in acinus ( A o CA ), and area of one acinar cell ( OAC ) were calculated. Results A significantly ( P < 0.05) increased A o CA , OAC , and DLA in labial glands from patients with impaired lipid metabolism, compared to controls, were found. Conclusion A positive relationship between dyslipidemia and morphological changes in labial salivary glands was obtained.