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Short‐ and long‐term potential effects of accelerated osteogenic orthodontic treatment: A systematic review and meta‐analysis
Author(s) -
Dab Sandeep,
Chen Kevin,
FloresMir Carlos
Publication year - 2019
Publication title -
orthodontics and craniofacial research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 55
eISSN - 1601-6343
pISSN - 1601-6335
DOI - 10.1111/ocr.12272
Subject(s) - meta analysis , term (time) , medicine , dentistry , orthodontics , physics , quantum mechanics
Structured Abstract Objective To better understand the potential effects after corticotomy accelerated osteogenic orthodontic treatment ( CAOOT ). Setting and sample population Systematic review with meta‐analysis. Materials and methods A literature search up to August 2018 was conducted to identify randomized clinical studies ( RCT s) on CAOOT reporting periodontal parameters, bone changes, patient‐centred and short‐ and long‐term adverse outcomes. A random‐effects meta‐analysis was performed on various parameters (bone density, buccal bone thickness, anchorage loss, visual analog scale, root resorption and retraction time) to quantify weighted treatment effects. Results A total of five split mouth, four parallel arms, one regular RCT s and two prospective CCT s were included (206 patients). Pooled data showed increase in bone thickness by 0.68 mm (95% CI : 1.17, 0.19) and reduced retraction time by 2.80 months (95% CI : −4.17, −1.43). There were statistically insignificant differences for root resorption 0.24 mm (95% CI : −0.49, 0.96), anchorage loss 0.49 mm (95% CI : −1.38, 0.40), worsening of periodontal parameters (gingival index) by 0.30 (95% CI : −0.83, 0.23) and mean increase in bone density of 7.07% on the corticotomy side at 6 months (95% CI : −3.24, 17.38). Conclusion Current evidence suggests a very low to low level of certainty ( GRADE assessment) in regard to quantified effects after CAOOT . Although CAOOT procedures show insignificant increase in the density following the use of bone graft and anchorage loss, they appear to accelerate the tooth movement during the first few months, to increase the buccal bone thickness and to show good tolerance by the patients; the clinical significance of these changes may be considered questionable.