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Morphological characteristics of frontal sinus and nasal bone focusing on bone resorption and apposition in hypophosphatemic rickets
Author(s) -
Gjørup H.,
Kjaer I.,
Sonnesen L.,
BeckNielsen S. S.,
Haubek D.
Publication year - 2013
Publication title -
orthodontics and craniofacial research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 55
eISSN - 1601-6343
pISSN - 1601-6335
DOI - 10.1111/ocr.12028
Subject(s) - frontal sinus , medicine , resorption , hypophosphatemic rickets , bone resorption , sinus (botany) , nasal bone , frontal bone , apposition , anatomy , dentistry , rickets , skull , biology , vitamin d and neurology , botany , genus
Structured Abstract Objectives To characterize the size and the morphology of the frontal sinus (i.e. , structure evolved by bone resorption) and the nasal bone (i.e., structure evolved by bone formation) in adults with hypophosphatemic rickets ( HR ) compared with controls. Setting and sample population Thirty‐six patients with HR (12 males and 24 females) aged 21–74 years were included. The control group comprised 49 healthy individuals (23 males and 26 females) aged 20–79 years. Material and methods Profile cephalograms were obtained and the following measurements were included: height and width of the frontal sinus; length, width, and area of the nasal bone. The morphology of the nasal bone was assessed. Linear regression analyses were used to compare HR patients with controls. Results In HR patients, the size of the frontal sinus was unaffected ( p = 0.406 to p = 0.862). The proximal width of the nasal bone, and the ratio between the proximal width and the axial length of the nasal bone were increased in HR patients ( p < 0.05). Conclusions The size of the frontal sinus was unaffected, indicating a normal ability of bone resorption within the bone. The morphology of the nasal bone was abnormal indicating a disturbance in bone formation during growth. The disturbances in nasal bone modeling were mainly expressed in the proximal part supported by structures of cartilaginous origin.