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Adiposity in relation to readmission and all‐cause mortality following coronary artery bypass grafting: A systematic review and meta‐analysis
Author(s) -
Zhang Kefeng,
Wang Junjie,
Yang Yan,
An Ruopeng
Publication year - 2019
Publication title -
obesity reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.845
H-Index - 162
eISSN - 1467-789X
pISSN - 1467-7881
DOI - 10.1111/obr.12855
Subject(s) - medicine , overweight , bypass grafting , obesity , odds ratio , mortality rate , cochrane library , obesity paradox , cinahl , meta analysis , cardiology , artery , psychological intervention , psychiatry
Summary This study systemically reviewed evidence linking adiposity to readmission and all‐cause mortality in post‐coronary artery bypass grafting (CABG) patients. Keyword/reference search was performed in PubMed, Web of Science, CINAHL, and Cochrane Library for articles published before June, 2018. Eligibility criteria included study designs: experimental/observational studies; subjects: adult patients undergoing CABG; and outcomes: hospital/clinic readmissions, and short‐term (≤30 days) and mid‐to‐long‐term (>30 days) all‐cause mortality. Seventy‐two studies were identified. Meta‐analysis showed that the odds of post‐CABG readmission among patients with overweight was 30% lower than their normal‐weight counterparts and the odds of mid‐to‐long‐term post‐CABG mortality among patients with overweight were 20% lower than their normal‐weight counterparts. In contrast, no difference in post‐CABG readmission rate was found between patients with obesity and their nonobese counterparts; no difference in short‐term or in‐hospital post‐CABG mortality rate was found between patients with overweight or obesity and their normal‐weight counterparts; and no difference in mid‐to‐long‐term post‐CABG mortality rate was found between patients with obesity and their normal‐weight counterparts. In conclusion, patients with overweight but not obesity had a lower readmission and mid‐to‐long‐term mortality rate following CABG relative to their normal‐weight counterparts. Preoperative weight loss may not be advised to patients with overweight undergoing CABG.