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Obesity and vitamin D deficiency: a systematic review and meta‐analysis
Author(s) -
PereiraSantos M.,
Costa P. R. F.,
Assis A. M. O.,
Santos C. A. S. T.,
Santos D. B.
Publication year - 2015
Publication title -
obesity reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.845
H-Index - 162
eISSN - 1467-789X
pISSN - 1467-7881
DOI - 10.1111/obr.12239
Subject(s) - medicine , vitamin d deficiency , overweight , obesity , observational study , vitamin , meta analysis , anthropometry , vitamin d and neurology , body mass index , endocrinology
Summary Over the past decade, there have been an increasing number of studies on the association between vitamin D deficiency and anthropometric state. However, we did not identify any meta‐analyses of the relationship between obesity and vitamin D deficiency in different age groups. Thus, we evaluated the association between obesity and vitamin D deficiency. We searched for observational studies published up to A pril 2014 in PubMed / M edline, W eb of S cience and S copus databases. We performed a meta‐analysis in accordance with the random‐effects model to obtain the summary measurement (prevalence ratio, PR). Among the 29,882 articles identified, 23 met the inclusion criteria. The prevalence of vitamin D deficiency was 35% higher in obese subjects compared to the eutrophic group ( PR : 1.35; 95% CI: 1.21–1.50) and 24% higher than in the overweight group ( PR : 1.24; 95% CI : 1.14–1.34). These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut‐offs to define vitamin D deficiency and the Human Development Index of the study location.