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Effect of childhood obesity prevention programmes on blood lipids: a systematic review and meta‐analysis
Author(s) -
Cai L.,
Wu Y.,
Cheskin L. J.,
Wilson R. F.,
Wang Y.
Publication year - 2014
Publication title -
obesity reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.845
H-Index - 162
eISSN - 1467-789X
pISSN - 1467-7881
DOI - 10.1111/obr.12227
Subject(s) - medicine , overweight , cochrane library , meta analysis , obesity , blood lipids , confidence interval , psychological intervention , randomized controlled trial , childhood obesity , cinahl , cholesterol , endocrinology , psychiatry
Summary We aimed to assess the effects of childhood obesity prevention programmes on blood lipids in high‐income countries. We searched MEDLINE ®, E mbase, P sych I nfo, CINAHL ®, clinicaltrials.gov , and the C ochrane L ibrary up to 22 A pril 2013 for relevant randomized controlled trials, quasi‐experimental studies and natural experiments published in E nglish. Studies were included if they implemented diet and/or physical activity intervention(s) with ≥1 year follow‐up (or ≥6 months for school‐based intervention studies) in 2–18‐year‐olds, and were excluded if they targeted only overweight/obese children, or those with a pre‐existing medical condition. Seventeen studies were finally included. For total cholesterol, the pooled intervention effect was −0.97 mg dL −1 [95% confidence interval ( CI ): −3.26, 1.32; P = 0.408]; for low‐density lipoprotein cholesterol ( LDL ‐ C ), −6.06 mg dL −1 (95% CI : −11.09, −1.02; P = 0.018); for high‐density lipoprotein cholesterol ( HDL ‐ C ), 1.87 mg dL −1 (95% CI : 0.39, 3.34; P = 0.013); and for triglycerides, −1.95 mg dL −1 (95% CI : −4.94, 1.04; P = 0.202). Most interventions (70%) showed similar significant or no effects on adiposity‐ and lipids outcomes: 15% interventions improved both adiposity‐ and lipids outcomes; 55% had no significant effects on either. Childhood obesity prevention programmes had a significant desirable effect on LDL ‐ C and HDL ‐ C . Two‐thirds of interventions showed similar significant or no effects in adiposity‐ and lipids outcomes. Assessing lipids outcomes provide additional useful information on obesity prevention programme benefits.