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Alternative therapies for GERD: a way to personalized antireflux surgery
Author(s) -
Rieder Erwin,
Riegler Martin,
Simić Aleksandar P.,
Skrobić Ognjan M.,
Bonavina Luigi,
Gurski Richard,
Paireder Matthias,
Castell Donald O.,
Schoppmann Sebastian F.
Publication year - 2018
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.13851
Subject(s) - gerd , medicine , disease , intensive care medicine , proton pump inhibitor , therapeutic window , pathological , population , therapeutic approach , surgery , reflux , pharmacology , environmental health
Gastroesophageal reflux disease (GERD) is a common disorder, known to affect about 20% of the Western population. Although conventional medical or surgical treatment has proven effective, there is certainly room for improvements. As only 10% of GERD patients are finally treated by antireflux surgery, a large therapeutic window exists. This treatment gap consists of patients who are not effectively treated with proton pump inhibitor but do not want to run the potential risks of conventional surgery. During the last two decades, several novel and intriguing options for the surgical treatment of GERD have been introduced and found their way into clinical use. The following summary will give an update of certain alternative therapeutic options to treat GERD or its pathological consequences.