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Resistance diagnosis and the changing economics of antibiotic discovery
Author(s) -
McAdams David
Publication year - 2017
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.13303
Subject(s) - antibiotics , antibiotic resistance , underpinning , profitability index , point (geometry) , risk analysis (engineering) , intensive care medicine , point of care , business , microbiology and biotechnology , medicine , biology , engineering , finance , mathematics , civil engineering , geometry , nursing
Point‐of‐care diagnostics that can determine an infection's antibiotic sensitivity increase the profitability of new antibiotics that enjoy patent protection, even when such diagnostics reduce the quantity of antibiotics sold. Advances in the science and technology underpinning rapid resistance diagnostics can therefore be expected to spur efforts to discover and develop new antibiotics, especially those with a narrow spectrum of activity that would otherwise fail to find a market.