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Acute stress and episodic memory retrieval: neurobiological mechanisms and behavioral consequences
Author(s) -
Gag Stephanie A.,
Wagner Anthony D.
Publication year - 2016
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12996
Subject(s) - episodic memory , cognitive psychology , psychology , effects of stress on memory , autobiographical memory , neuroscience , function (biology) , stress (linguistics) , affect (linguistics) , recall , hippocampus , cognition , memory consolidation , communication , linguistics , philosophy , evolutionary biology , biology
Episodic retrieval allows people to access memories from the past to guide current thoughts and decisions. In many real‐world situations, retrieval occurs under conditions of acute stress, either elicited by the retrieval task or driven by other, unrelated concerns. Memory under such conditions may be hindered, as acute stress initiates a cascade of neuromodulatory changes that can impair episodic retrieval. Here, we review emerging evidence showing that dissociable stress systems interact over time, influencing neural function. In addition to the adverse effects of stress on hippocampal‐dependent retrieval, we consider how stress biases attention and prefrontal cortical function, which could further affect controlled retrieval processes. Finally, we consider recent data indicating that stress at retrieval increases activity in a network of brain regions that enable reflexive, rapid responding to upcoming threats, while transiently taking offline regions supporting flexible, goal‐directed thinking. Given the ubiquity of episodic memory retrieval in everyday life, it is critical to understand the theoretical and applied implications of acute stress. The present review highlights the progress that has been made, along with important open questions.