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Evolution of small guide RNA genes in hyperthermophilic archaea
Author(s) -
Randau Lennart
Publication year - 2015
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12643
Subject(s) - rna , archaea , biology , genetics , non coding rna , small nucleolar rna , gene , rna splicing , base pair , small nuclear rna , genome , ribosomal rna , long non coding rna , computational biology
Profiling the RNA production in hyperthermophilic archaea revealed an abundance of small RNA–guided processes near the upper temperature limit of life. Archaea utilize the base‐pairing ability of RNA guide sequences to target ribosomal RNAs, transfer RNAs, messenger RNAs, and viral genomes. Cellular processes that are guided by small RNAs include the modification of RNA molecules, trans ‐splicing, gene regulation, and RNA and DNA degradation. Here, a brief overview of our knowledge on small guide RNA genes in archaeal genomes is provided and examples of their putative roles in genome evolution are described.