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Adenocarcinoma at the gastroesophageal junction
Author(s) -
AlHaddad Sahar,
Chang Andrew C.,
De Hertogh Gert,
Grin Andrea,
Langer Rupert,
Sagaert Xavier,
Salemme Marianna,
Streutker Catherine J.,
Soucy Geneviève,
Tripathi Monika,
Upton Melissa P.,
Vieth Michael,
Villanacci Vincenzo
Publication year - 2014
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12535
Subject(s) - adenocarcinoma , esophagus , gastroesophageal junction , intestinal metaplasia , medicine , metaplasia , immunohistochemistry , esophagogastric junction , pathology , gastric cardia , gastroenterology , stomach , cancer
The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the clinical differences between carcinomas arising slightly above, slightly below, and within the gastroesophageal junction (GEJ); information provided by biopsies; information provided by resection specimens following neoadjuvant therapy; histologic differences existing between carcinomas arising slightly above, slightly below, and within the GEJ; differences provided by immunohistochemistry in these tumors; information given by endoscopic mucosal resection specimens; the role of esophageal pyloric gland adenomas as precursors of adenocarcinomas in the region of the cardia; the role of pancreatic metaplasia; Her2 immunoreactivity to make distinctions in the site of origin; and intestinal metaplasia limited to the cardia as a precursor of adenocarcinoma.