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Causes and treatments of achalasia, and primary disorders of the esophageal body
Author(s) -
Felix Valter Nilton,
DeVault Kenneth,
Penagini Roberto,
Elvevi Alessandra,
Swanstrom Lee,
Wassenaar Eelco,
Crespin Oscar M.,
Pellegrini Carlos A.,
Wong Roy
Publication year - 2013
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12254
Subject(s) - achalasia , myotomy , esophageal motility disorder , medicine , esophageal sphincter , esophageal spasm , high resolution manometry , esophagus , heller myotomy , esophageal disorder , surgery , gastroenterology , reflux , disease
The following on achalasia and disorders of the esophageal body includes commentaries on controversies regarding whether patients with complete lower esophageal sphincter (LES) relaxation can be considered to exhibit early achalasia; the roles of different mucle components of the LES in achalasia; sensory neural pathways impaired in achalasia; indications for peroral endoscopic myotomy and advantages of the technique over laparoscopic and thorascopic myotomy; factors contributing to the success of surgical therapy for achalasia; modifications to the classification of esophageal body primary motility disorders in the advent of high‐resolution manometry (HRM); analysis of the LES in differentiating between achalasia and diffuse esophageal spasm (DES); and appropriate treatment for DES, nutcracker esophagus (NE), and hypertensive LES (HTLES).