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Laryngopharyngeal reflux and GERD
Author(s) -
Johnston Nikki,
Dettmar Peter W.,
Strugala Vicki,
Allen Jacqui E.,
Chan Walter W.
Publication year - 2013
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12237
Subject(s) - laryngopharyngeal reflux , pepsin , gerd , indigestion , medicine , reflux , etiology , gastroenterology , chronic cough , swallowing , proton pump inhibitor , disease , asthma , surgery , chemistry , enzyme , biochemistry
In patients with laryngopharygeal reflux (LPR), gastric contents exhibit retrograde flow into the upper aero‐digestive tract, causing extraesophageal symptoms including chronic cough, hoarseness, indigestion, difficulty swallowing, globus pharyngis, and asthma. The following on laryngopharyngeal reflux includes commentaries on the use of patient‐completed questionaires and anti‐human pepsin antibodies and other non‐invasive tests in diagnosis; the role of pepsin and acid in the etiologies of laryngeal cancers; and the application of proton pump inhibitor (PPI) therapy for the treatment of LPR.