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Molecular, genetic, cellular, and network functions in the spinal cord and brainstem
Author(s) -
Stein Paul S.G.
Publication year - 2013
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/nyas.12083
Subject(s) - brainstem , neuroscience , spinal cord , neurogenetics , biology , nervous system , connectome , functional connectivity , genetics , gene
Studies of the model systems of spinal cord and brainstem reveal molecular, genetic, and cellular mechanisms that are critical for network and behavioral functions in the nervous system. Recent experiments establish the importance of neurogenetics in revealing cellular and network properties. Breakthroughs that utilize direct visualization of neuronal activity and network structure provide new insights. Major discoveries of plasticity in the spinal cord and brainstem contribute to basic neuroscience and, in addition, have promising therapeutic implications.