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Arabidopsis acyl‐CoA‐binding proteins regulate the synthesis of lipid signals
Author(s) -
Lung ShiuCheung,
Chye MeeLen
Publication year - 2019
Publication title -
new phytologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.742
H-Index - 244
eISSN - 1469-8137
pISSN - 0028-646X
DOI - 10.1111/nph.15707
Subject(s) - arabidopsis , phosphatidic acid , sphingolipid , lipid signaling , biochemistry , biology , gene isoform , acyl coa , signal transduction , microbiology and biotechnology , lipid metabolism , chemistry , receptor , enzyme , gene , phospholipid , mutant , membrane
Summary Plant lipid signals are crucial developmental modulators and stress response mediators. A family of acyl‐CoA‐binding proteins ( ACBP s) participates in the lipid trafficking of these signals. Isoform‐specific functions can arise from differences in their subcellular distribution, tissue‐specificity, stress‐responsiveness, and ligand selectivity. In lipid‐mediated cell signaling, plant ACBP s are not merely transporters but are also important regulators via their interaction with lipid‐metabolic enzymes and precursor lipids. In this Insight, the regulatory roles of plant ACBP s in the synthesis of various signaling lipids, including phosphatidic acid, sterols, oxylipins, and sphingolipids, are reviewed. We focus on the functional significance of these lipid signals in plant development and stress responses with an overview of recent work using reverse genetics and transgenic Arabidopsis.