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Multiple strategies for pathogen perception by plant immune receptors
Author(s) -
Cesari Stella
Publication year - 2018
Publication title -
new phytologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.742
H-Index - 244
eISSN - 1469-8137
pISSN - 0028-646X
DOI - 10.1111/nph.14877
Subject(s) - biology , computational biology , plant disease resistance , immune system , architecture domain , neuroscience , genetics , architecture , gene , art , enterprise architecture management , enterprise architecture , visual arts
ContentsSummary 17 I. Introduction 17 II. Pathogen perception by NLRs: from direct recognition to integrated decoys 18 III. Multiple activation and signaling pathways for NLRs 18 IV. How to engineer NLR‐mediated disease resistance? 21 V. Conclusion 23Acknowledgements 23References 23Summary Plants have evolved a complex immune system to protect themselves against phytopathogens. A major class of plant immune receptors called nucleotide‐binding domain and leucine‐rich repeat‐containing proteins ( NLR s) is ubiquitous in plants and is widely used for crop disease protection, making these proteins critical contributors to global food security. Until recently, NLR s were thought to be conserved in their modular architecture and functional features. Investigation of their biochemical, functional and structural properties has revealed fascinating mechanisms that enable these proteins to perceive a wide range of pathogens. Here, I review recent insights demonstrating that NLR s are more mechanistically and structurally diverse than previously thought. I also discuss how these findings provide exciting future prospects to improve plant disease resistance.