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APETALA 2/Ethylene Responsive Factor ( AP 2/ ERF ) transcription factors: mediators of stress responses and developmental programs
Author(s) -
Licausi Francesco,
OhmeTakagi Masaru,
Perata Pierdomenico
Publication year - 2013
Publication title -
new phytologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.742
H-Index - 244
eISSN - 1469-8137
pISSN - 0028-646X
DOI - 10.1111/nph.12291
Subject(s) - transcription factor , biology , microbiology and biotechnology , genetics , transcription (linguistics) , computational biology , gene , linguistics , philosophy
Summary Transcription factors belonging to the APETALA 2/Ethylene R esponsive F actor ( AP 2/ ERF ) family are conservatively widespread in the plant kingdom. These regulatory proteins are involved in the control of primary and secondary metabolism, growth and developmental programs, as well as responses to environmental stimuli. Due to their plasticity and to the specificity of individual members of this family, AP 2/ ERF transcription factors represent valuable targets for genetic engineering and breeding of crops. In this review, we integrate the evidence collected from functional and structural studies to describe their different mechanisms of action and the regulatory pathways that affect their activity.